Biodegradable and pH-sensitive polymersome with tuning permeable membrane for drug delivery carrier.
نویسندگان
چکیده
Novel biodegradable and pH-sensitive polymersomes prepared from poly(ethylene glycol) and poly(d,l-lactide) grafted poly(beta-amino ester) exhibit pH dependent permeability on hydrophilic solutes of which permeability is determined by the packing state of poly(d,l-lactide) membrane followed by ionization of poly(beta-amino ester) inducing loosely packed membrane formation from well-ordered packing.
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 25 شماره
صفحات -
تاریخ انتشار 2010